Frequently Asked Questions
Find answers to common questions about Calmare/Scrambler Therapy, treatment protocols, clinical studies and what to expect.
Understanding the Provider Map
Understanding the Provider Map
Our Calmare/Scrambler Therapy Provider Locator Map is the most comprehensive directory of providers available for the U.S. Here's how to use it effectively:
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Use the filter to find providers based upon certification type
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Reach out to the chosen provider to schedule a free consultation!
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Search by Location
Enter your zip code or city to find nearby providers
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Search by Location
Enter your zip code or city to find nearby providers
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Review Provider Details
Click on markers to see contact information and specialties
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Review Provider Details
Click on markers to see contact information and specialties
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Filter by Condition
Use filters to find providers specializing in your condition
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Filter by Condition
Use filters to find providers specializing in your condition
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Contact Directly
Reach out to schedule a consultation and discuss your needs
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Contact Directly
Reach out to schedule a consultation and discuss your needs
Patient Blogs
A Journey from CRPS Diagnosis to Wellness: My Story
Chronic pain can be isolating, confusing, and exhausting. When an ankle injury lingered far longer than it should have.
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A Journey from CRPS Diagnosis to Wellness: My Story
Chronic pain can be isolating, confusing, and exhausting. When an ankle injury lingered far longer than it should have.
Read More
A Journey from CRPS Diagnosis to Wellness: My Story
Chronic pain can be isolating, confusing, and exhausting. When an ankle injury lingered far longer than it should have.
Read More
Calmare/Scrambler Therapy vs. TENS: What is the Difference, What the Evidence Says, and How They Interact
If you’re exploring non-pharmacologic options for chronic pain, you’ve likely come across two terms that sound similar..
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Calmare/Scrambler Therapy vs. TENS: What is the Difference, What the Evidence Says, and How They Interact
If you’re exploring non-pharmacologic options for chronic pain, you’ve likely come across two terms that sound similar..
Read More
Calmare/Scrambler Therapy vs. TENS: What is the Difference, What the Evidence Says, and How They Interact
If you’re exploring non-pharmacologic options for chronic pain, you’ve likely come across two terms that sound similar..
Read More
CRPS: Navigating the Maze of Doctors and Appointments
When you’re first diagnosed with a complex condition like CRPS (or any chronic illness), it’s easy to feel lost in a....
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CRPS: Navigating the Maze of Doctors and Appointments
When you’re first diagnosed with a complex condition like CRPS (or any chronic illness), it’s easy to feel lost in a....
Read More
CRPS: Navigating the Maze of Doctors and Appointments
When you’re first diagnosed with a complex condition like CRPS (or any chronic illness), it’s easy to feel lost in a....
Read More
Read More Blogs
Clinical Studies and Trials
Calmare Scrambler Therapy is a non-invasive, FDA-approved treatment designed to alleviate chronic pain by disrupting pain signals through the application of electrical stimulation. Over the past decade, numerous clinical studies and trials have been conducted to evaluate its efficacy, safety, and potential as an alternative to pharmacological pain management. These investigations have explored a variety of chronic pain conditions, including neuropathy, cancer-related pain, and post-surgical pain, providing valuable insights into the therapy’s mechanisms and clinical benefits. Below is a compilation of notable studies and trials that have contributed to the growing body of evidence supporting Calmare Scrambler Therapy.
Mayo Clinic
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“There are now more than 60 scrambler therapy (or Calmare, 1 trade name) citations listed in PubMed, including successful randomized trials. It is used extensively in the military with good success, especially with neuropathic pain and at experienced pain management centers." Mayo Clinic Proceedings (2021)
Mayo Clinic
Successful Treatment With Scrambler Therapy for Radial and Femoral Nerve Injuries After Extracorporeal Membrane Oxygenation-
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Successful Treatment With Scrambler Therapy for Radial and Femoral Nerve Injuries After Extracorporeal Membrane Oxygenation-
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Successful Treatment With Scrambler Therapy for Radial and Femoral Nerve Injuries After Extracorporeal Membrane Oxygenation-
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Randomized Trial of Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy: Crossover Analysis-
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Randomized Trial of Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy: Crossover Analysis-
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Randomized Trial of Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy: Crossover Analysis-
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A Study Comparing Scrambler Therapy versus TENS Therapy in Treating Patients with Chemotherapy-Induced Peripheral Neuropathy-
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A Study Comparing Scrambler Therapy versus TENS Therapy in Treating Patients with Chemotherapy-Induced Peripheral Neuropathy-
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A Study Comparing Scrambler Therapy versus TENS Therapy in Treating Patients with Chemotherapy-Induced Peripheral Neuropathy-
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Moving Beyond a Painful Decade – New Technology Offers Respite From Debilitating Leg Pain-
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Moving Beyond a Painful Decade – New Technology Offers Respite From Debilitating Leg Pain-
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Moving Beyond a Painful Decade – New Technology Offers Respite From Debilitating Leg Pain-
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Breaking Away From Pain With the Help of ‘The Scrambler-
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Breaking Away From Pain With the Help of ‘The Scrambler-
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Breaking Away From Pain With the Help of ‘The Scrambler-
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Sidelined No More – Scrambler Therapy Puts Tess Wilson Back in Action-
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Sidelined No More – Scrambler Therapy Puts Tess Wilson Back in Action-
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Sidelined No More – Scrambler Therapy Puts Tess Wilson Back in Action-
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Universities
Scrambler Therapy for Post-Stroke Pain-
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Scrambler Therapy for Post-Stroke Pain-
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Scrambler Therapy for Post-Stroke Pain-
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Scrambler therapy may offer lasting relief for chronic pain, Johns Hopkins review suggests-
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Scrambler therapy may offer lasting relief for chronic pain, Johns Hopkins review suggests-
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Scrambler therapy may offer lasting relief for chronic pain, Johns Hopkins review suggests-
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The Use of Scrambler Therapy in Treating Chronic Pain Syndromes: A Systematic Review-
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The Use of Scrambler Therapy in Treating Chronic Pain Syndromes: A Systematic Review-
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The Use of Scrambler Therapy in Treating Chronic Pain Syndromes: A Systematic Review-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy-induced peripheral neuropathy in adolescents: A preliminary study-
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Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy-induced peripheral neuropathy in adolescents: A preliminary study-
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Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy-induced peripheral neuropathy in adolescents: A preliminary study-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial-
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Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial-
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Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial-
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Decreased low back pain intensity and differential gene expression following Calmare®: results from a double-blinded randomized sham-controlled study-
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Decreased low back pain intensity and differential gene expression following Calmare®: results from a double-blinded randomized sham-controlled study-
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Decreased low back pain intensity and differential gene expression following Calmare®: results from a double-blinded randomized sham-controlled study-
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Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis-
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Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis-
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Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis-
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Scrambler therapy improves pain in neuromyelitis optica: A randomized controlled trial-
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Scrambler therapy improves pain in neuromyelitis optica: A randomized controlled trial-
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Scrambler therapy improves pain in neuromyelitis optica: A randomized controlled trial-
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New England Journal of Medicine
Cutaneous Electroanalgesia for Relief of Chronic and Neuropathic Pain-
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Cutaneous Electroanalgesia for Relief of Chronic and Neuropathic Pain-
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Cutaneous Electroanalgesia for Relief of Chronic and Neuropathic Pain-
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Some of the largest reviews and reports indicate that 10 to 20% of patients have no analgesic response to scrambler therapy, whereas approximately 80 to 90% have a favorable response."
Leading Hospitals and Publications
Scrambler therapy for treatment of poststroke pain-
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Scrambler therapy for treatment of poststroke pain-
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Scrambler therapy for treatment of poststroke pain-
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Scrambler Therapy for Treating Neuropathic Pain-
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Scrambler Therapy for Treating Neuropathic Pain-
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Scrambler Therapy for Treating Neuropathic Pain-
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Revolutionizing Neuropathic Symptom Relief with Scrambler Technology-
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Revolutionizing Neuropathic Symptom Relief with Scrambler Technology-
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Revolutionizing Neuropathic Symptom Relief with Scrambler Technology-
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7 pain management options for cancer patients you might not know about-
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7 pain management options for cancer patients you might not know about-
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7 pain management options for cancer patients you might not know about-
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Scrambler therapy for incident pain in bone metastases-
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Scrambler therapy for incident pain in bone metastases-
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Scrambler therapy for incident pain in bone metastases-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Treatment of post-herpetic pain with scrambler therapy, a patient-specific neuro-cutaneous electrical stimulation device-
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Treatment of post-herpetic pain with scrambler therapy, a patient-specific neuro-cutaneous electrical stimulation device-
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Treatment of post-herpetic pain with scrambler therapy, a patient-specific neuro-cutaneous electrical stimulation device-
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Cancer pain management brings patients relief-
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Cancer pain management brings patients relief-
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Cancer pain management brings patients relief-
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Calmare Therapy – An Innovative Pain Treatment: What Is It?-
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Calmare Therapy – An Innovative Pain Treatment: What Is It?-
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Calmare Therapy – An Innovative Pain Treatment: What Is It?-
View Study
Common Questions
What does Scrambler Therapy feel like?
Most patients experience a tingling, biting or buzzing feeling at the electrode sites. The discomfort should subside quickly and then a feeling of a hum will set in. The treatment is generally well tolerated and most fine the therapy to be relaxing and pleasant.
What does Scrambler Therapy feel like?
Most patients experience a tingling, biting or buzzing feeling at the electrode sites. The discomfort should subside quickly and then a feeling of a hum will set in. The treatment is generally well tolerated and most fine the therapy to be relaxing and pleasant.
What does Scrambler Therapy feel like?
Most patients experience a tingling, biting or buzzing feeling at the electrode sites. The discomfort should subside quickly and then a feeling of a hum will set in. The treatment is generally well tolerated and most fine the therapy to be relaxing and pleasant.
Should I do anything to prepare for treatment?
Should I do anything to prepare for treatment?
Should I do anything to prepare for treatment?
Can I be on medications when being treated with Scrambler Therapy?
Can I be on medications when being treated with Scrambler Therapy?
Can I be on medications when being treated with Scrambler Therapy?
What should I wear during Scrambler Therapy treatment?
What should I wear during Scrambler Therapy treatment?
What should I wear during Scrambler Therapy treatment?
How long is the treatment and how long does a Scrambler Therapy session last?
How long is the treatment and how long does a Scrambler Therapy session last?
How long is the treatment and how long does a Scrambler Therapy session last?
Are there any contraindications for Scrambler Therapy?
Are there any contraindications for Scrambler Therapy?
Are there any contraindications for Scrambler Therapy?
Can Scrambler Therapy be used alongside any other pain management treatments?
Can Scrambler Therapy be used alongside any other pain management treatments?
Can Scrambler Therapy be used alongside any other pain management treatments?
How much does Scrambler Therapy Cost?
How much does Scrambler Therapy Cost?
How much does Scrambler Therapy Cost?