Frequently Asked Questions
Find answers to common questions about Calmare®/Scrambler Therapy, how to use the provider locator map, treatment protocols, clinical studies and what to expect.
Calmare Certified™ treatment facilities are locations whose healthcare professionals have completed a comprehensive training regimen provided by Calmare's trainer with over 15 years of experience, Brandi Marino. Calmare Certified treatment facilities have satisfied specific certification requirements and demonstrate a continuing expertise with Calmare Pain Therapy Treatment. This certification complies with a continuing effort to meet FDA quality requirements.
Scrambler Therapy Certified™ - Similar training program as Calmare, however it is unclear who the trainer is.
Not Certified - We found no record of any formal training or certifications in the field of light therapy or scrambler therapy for this provider.
Common Questions
Patient & Provider Blogs
Why There’s No Standard Curriculum for Scrambler Therapy (And Why That Matters for Patients)
If you’ve been researching Scrambler Therapy® — also known as Calmare® Therapy, you may have noticed no two providers..
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Inside My Calmare Scrambler Therapy Training Experience
This past week I have spent immersed in training focused on Calmare Scrambler Therapy, one of the most innovative non-in
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Calmare®/Scrambler Therapy for Peripheral Neuropathy: A New Way to Calm Nerve Pain
Peripheral neuropathy can be exhausting, frustrating, and life-limiting. Burning, tingling, electric shocks, numbness...
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Read More Blogs
Clinical Studies and Trials
Calmare®/Scrambler Therapy is a non-invasive, FDA-approved treatment designed to alleviate chronic pain by disrupting pain signals through the application of electrical stimulation. Over the past decade, numerous clinical studies and trials have been conducted to evaluate its efficacy, safety, and potential as an alternative to pharmacological pain management. These investigations have explored a variety of chronic pain conditions, including neuropathy, cancer-related pain, and post-surgical pain, providing valuable insights into the therapy’s mechanisms and clinical benefits. Below is a compilation of notable studies and trials that have contributed to the growing body of evidence supporting Calmare Scrambler Therapy.
Mayo Clinic
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“There are now more than 60 scrambler therapy (or Calmare, 1 trade name) citations listed in PubMed, including successful randomized trials. It is used extensively in the military with good success, especially with neuropathic pain and at experienced pain management centers." Mayo Clinic Proceedings (2021)
Mayo Clinic
Successful Treatment With Scrambler Therapy for Radial and Femoral Nerve Injuries After Extracorporeal Membrane Oxygenation-
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Randomized Trial of Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy: Crossover Analysis-
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A Study Comparing Scrambler Therapy versus TENS Therapy in Treating Patients with Chemotherapy-Induced Peripheral Neuropathy-
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Moving Beyond a Painful Decade – New Technology Offers Respite From Debilitating Leg Pain-
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Breaking Away From Pain With the Help of ‘The Scrambler-
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Sidelined No More – Scrambler Therapy Puts Tess Wilson Back in Action-
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Universities
Scrambler Therapy for Post-Stroke Pain-
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Scrambler therapy may offer lasting relief for chronic pain, Johns Hopkins review suggests-
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The Use of Scrambler Therapy in Treating Chronic Pain Syndromes: A Systematic Review-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy-induced peripheral neuropathy in adolescents: A preliminary study-
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The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial-
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Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial-
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Decreased low back pain intensity and differential gene expression following Calmare®: results from a double-blinded randomized sham-controlled study-
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Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis-
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Scrambler therapy improves pain in neuromyelitis optica: A randomized controlled trial-
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New England Journal of Medicine
Cutaneous Electroanalgesia for Relief of Chronic and Neuropathic Pain-
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Some of the largest reviews and reports indicate that 10 to 20% of patients have no analgesic response to scrambler therapy, whereas approximately 80 to 90% have a favorable response."
Leading Hospitals and Publications
Scrambler therapy for treatment of poststroke pain-
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Scrambler Therapy for Treating Neuropathic Pain-
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Revolutionizing Neuropathic Symptom Relief with Scrambler Technology-
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7 pain management options for cancer patients you might not know about-
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Scrambler therapy for incident pain in bone metastases-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device-
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Scrambler Therapy Benefit in Cancer-Related Neuropathic Pain-
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Treatment of post-herpetic pain with scrambler therapy, a patient-specific neuro-cutaneous electrical stimulation device-
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Cancer pain management brings patients relief-
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Calmare Therapy – An Innovative Pain Treatment: What Is It?-
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