Scrambler Therapy or Calmare® Therapy was developed in Italy in 2003 by Dr. Giuseppe Marineo, a neurophysiologist. It utilizes an FDA certified, patented device that sends non-painful electrical signals through the skin to "scramble" the pain signals being sent to the brain. This mechanism effectively alters how the brain perceives pain, allowing for relief without the use of medication.

The therapy emerged from the need to find effective treatments for patients suffering from chronic pain conditions, particularly those unresponsive to standard pain management techniques. Dr. Marineo's research focused on how pain signals are transmitted through the nervous system and how they can be disrupted. Some of the largest reviews to date indicate that approximately 80% of patients have some form of a favorable response, making Calmare®/Scrambler Therapy a game-changer for the management for chronic nerve pain!